Best Compounding Pharmacy for Semaglutide
Compounded semaglutide offers a more affordable alternative to brand-name medications. Understanding how to identify quality compounding pharmacies is crucial for safety and effectiveness.
The Quick Answer: IMPORTANT: As of May 2025, FDA enforcement discretion for compounded semaglutide has ended. Compounded semaglutide is no longer legally available except in rare individualized cases. Consider FDA-approved Ozempic/Wegovy or telehealth providers with pricing assistance. While compounding was available, 503B facilities with sterility testing were safest—but 96% failed FDA inspections.
Providers Using Quality Compounding Pharmacies
These telehealth providers partner with accredited compounding pharmacies for semaglutide.
CoreAge Rx
Premium GLP-1 Weight Loss Program
- U.S. Board-Certified Physician Oversight
- Free 2-Day Shipping Included
- Up to 15% Body Weight Loss Potential
Super Healthy Rx
Simple Online Wellness with Transparent Pricing
- Transparent Pricing: $299 Sema, $399 Tirz
- No Insurance Required, No Hidden Fees
- Free Shipping Included
Mochi Health
Meds start at $99/mo, No Long-Term Commitment
- Affordable: $99/mo Semaglutide, $199/mo Tirzepatide
- Registered Dietitian Support Included
- 24/7 Messaging Access to Care Team
REGULATORY UPDATE: May 2025
FDA enforcement discretion for compounded semaglutide ended May 22, 2025.Compounded semaglutide is no longer legally available except in rare individualized cases (e.g., patients with specific allergies to brand-name ingredients).
In August 2024, ProRx recalled over 13,000 vials of compounded semaglutide due to questionable sterility. Of 55 inspected 503B facilities, 96% received FDA citations for inspection issues. FDA warned that non-sterile injectable drugs can cause life-threatening infections and sepsis.
This article provides historical context on compounding quality standards. For current options, see FDA-approved Ozempic/Wegovy or telehealth providers offering pricing assistance.
What Is Compounded Semaglutide?
Compounded semaglutide is made by licensed compounding pharmacies using the same active ingredient as brand-name medications like Wegovy and Ozempic. It's legally available when brand-name versions are in shortage or unaffordable for patients.
Advantages
- • Significantly lower cost
- • Available during shortages
- • Custom dosing options
- • Same active ingredient
Considerations
- • Not FDA-approved as a product
- • Quality varies by pharmacy
- • Requires prescription
- • Not covered by insurance
How to Identify a Quality Compounding Pharmacy
Not all compounding pharmacies meet the same quality standards. Look for these key indicators:
503B Registration
503B outsourcing facilities are registered with the FDA and subject to more rigorous oversight than traditional 503A pharmacies. They can produce larger quantities and must follow current Good Manufacturing Practices (cGMP).
PCAB Accreditation
The Pharmacy Compounding Accreditation Board (PCAB) provides voluntary accreditation for compounding pharmacies that meet high quality standards.
Third-Party Testing
Quality pharmacies perform potency and sterility testing on their products and can provide certificates of analysis upon request.
Questions to Ask About Compounded Semaglutide
- 1.Is the compounding pharmacy 503A or 503B registered?
- 2.Does the pharmacy have PCAB or other accreditation?
- 3.Is third-party potency and sterility testing performed?
- 4.What is the source of the active pharmaceutical ingredient?
- 5.What is the beyond-use date (expiration) of the medication?
- 6.How is the medication shipped to maintain stability?